Attrition in the therapeutic pipeline can often be associated with the lack of translational efficacy from the pre-clinical phase to the clinic. Organoids demonstrate the significant potential to ...

Discovery of efficient anti-cancer drugs and drug combinations is essential for therapy success. Therefore, it is crucial that new methods for efficient drug efficacy testing are developed to support ...

Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...

Article reviewed by Julía Crispim da Fontoura, a PhD candidate at the Federal University of Health Sciences of Porto Alegre, Brazil who uses organoids to study drug resistance. Stay up to date on the ...

To permanently access this Application Compendium for free, fill out the short form below. Discover the continued innovation in imaging and microscopy with Agilent's detailed application compendium on ...

In a recent article published in Scientific Reports, researchers used a multimodal imaging approach to study type I collagen 3D cell culture models, focusing on interactions between human dermal ...

Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes. These two-dimensional cultures distort cell behavior, limiting ...