The San Francisco 49ers upset the Philadelphia Eagles with a remarkable defensive effort and a come-from-behind win.

Visit ESPN for San Francisco 49ers live scores, video highlights, and latest news. Find standings and the full 2025 season schedule.

It's over at Lumen Field for real this time. The Seattle Seahawks blew out the San Francisco 49ers 41-6 at Lumen Field and earned a trip to the NFC championship game. Meanwhile, the 49ers will try and ...

The Los Angeles Rams are set to acquire an All-Pro in a trade, and it puts more pressure on the San Francisco 49ers to be ...

San Francisco 49ers DL C.J. West sacks Seattle Seahawks QB Sam Darnold for an 8-yard loss during the NFC Divisional Round of the 2025 NFL season. San Francisco 49ers K Eddy Piñeiro made a 56-yard ...

San Francisco 49ers wide receiver Mike Evans talks to reporters about why he decided to sign with the 49ers in free agency.

With the NFL Scouting Combine complete in Indianapolis, analysts are updating their 2026 NFL mock drafts based on workout data and team needs. A clear theme has emerged for the 49ers: add an offensive ...

The San Francisco 49ers selected 11 players in the 2025 NFL Draft, and cornerback Upton Stout may have emerged as the most impactful of the group. As a rookie, Stout appeared in 16 games, made four ...