The B.1.1.7 variant of SARS-CoV-2 first detected in the UK harbors amino-acid substitutions and deletions in the spike protein that potentially enhance host angiotensin conversion enzyme 2 (ACE2) ...
Overall, in this study, we found that the mutations in the B.1.1.7 S protein can significantly enhance its viral fusion activity and its infectivity. Based on the structure of the B.1.1.7 ...