Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies ...

A research team at Sejong University's Plant Immunity Laboratory, led by Professor Nam-Soo Jwa, has uncovered an important ...

Researchers have identified how a single mutation in the GPX4 enzyme causes neurons to undergo ferroptosis, leading to severe early-onset dementia.

Two enzymes from the protein disulphide isomerase (PDI) family enable prostate cancer cells to grow, survive, and resist treatment. This discovery, however, could be taken as an advantage to improve ...

Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's. The team has identified a small ...

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it. However, the molecular mechanisms ...

Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes ...

In a new study, researchers have identified a way to stop cells from dying, opening the door to developing treatments that slow the progression of neurodegenerative conditions like Parkinson’s disease ...

The structure of the ‘cell killer’ protein called BAX, that WEHI researchers have discovered how to block. Researchers have discovered how to block cells dying, in a finding that could lead to new ...