For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

The ciliary body (CB) has been proposed as a niche of neural stem cells because, in vitro, cells from this area are able to form neurospheres, proliferate and differentiate. Here, we explore the ...

Understanding how our cells function in health and disease is essential both for basic human biology and for medical advances in diagnosis and treatment. While genetic studies have mapped more than ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...

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Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

An international team of researchers led by Max Delbrück Center Scientific Director Professor Maike Sander, MD, has for the first time developed an organoid model of human pluripotent stem ...

A growing body of research is challenging the long-held assumption that memory and awareness belong exclusively to the brain. Scientists working across immunology, biophysics, and neuroscience have ...

Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four ...