Throughout our lives, our bones are continuously remodeled to maintain strength, repair injuries and adapt to new stresses. Bone dynamics depend on two associated cell types: osteoblasts, which are ...

An international collaboration study reveals how evolution and locomotion patterns, such as bipedalism, shaped bone structures through proteins present in the bone matrix. The findings of the study, ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Bone is continuously renewed through a process known as bone remodeling, in which osteoblasts (bone-forming cells) build new bone, while osteoclasts (bone-resorbing cells) remove older mineralized ...

A multidisciplinary research team has developed a technique to replicate bone tissue complexity and bone-remodeling processes. This breakthrough could help researchers further their study of bone ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling—a ...

This diagram illustrates the role of macrophage ATF6 in orthodontic tooth movement. When corticotomy is applied, monocytes are recruited to the bone, where they differentiate into pro-inflammatory ...

When you fracture a bone, the injury sets off a very intricate and lengthy healing process. Bones are tough, but they’re not able to heal from a fracture in a day, a week, or even a month. It takes ...

A multidisciplinary team of researchers at the University of Massachusetts Amherst's Institute for Applied Life Sciences (IALS) have developed a technique to replicate bone tissue complexity and bone ...

Fam102a-Rbpjl axis in osteoblast differentiation reveals significant insights into bone remodeling and may aid the development of therapeutic strategies. Bones are the living tissue on which the human ...