Bone tissue engineering (BTE) has emerged as a critical solution for repairing large bone defects caused by trauma, infection ...

Bone tissue is generally resilient and can self-heal, but critical-size defects (CSDs) with complex geometries cannot be repaired without clinical intervention. Customized scaffolds developed using ...

Key factors in bone repair depend on the healing tissue’s local mechanical environment. A study by Isaksson et al. 1 examined computational mechanobiology in bone healing, revealing variables such as ...

Scientists at the University of Glasgow developed a bioengineered bone marrow (BM) model that helped them to evaluate potential use of a combined CRISPR-CAR T cell therapy in the treatment of acute ...

Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

Scientists at the University of Glasgow have successfully used the first bioengineered bone marrow model to carry out vital cancer research, offering new insights into potential therapies for the ...

A new, easily adopted, 3D-printed device will enable scientists to create models of human tissue with even greater control and complexity. An interdisciplinary group of researchers at the University ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...