Understanding the mechanism by which cell growth, migration, polyploidy, and tumorigenesis are regulated may provide important therapeutic strategies for cancer therapy. Here we identify the ...
New York and Hong Kong, April 12, 2023 (GLOBE NEWSWIRE) -- Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced that ...
Based on the structure and binding mode of existent molecules, Insilico’s R&D team used Chemistry42, the small molecule generation and design platform integrating more than 40 generative models, to ...
The transcription-associated kinases CDK7, CDK8/19, and CDK9 are essential for development and normal physiological function, and altered function of each kinase is broadly implicated in myriad human ...
Most cancers are caused by a large variety of factors that vary from one person to another. To unravel this complexity, genes that contribute to the development of a respective cancer must be ...
Researchers have found that treating prostate cancer cells with novel cyclin-dependent kinase 19 (CDK19) and homologous cyclin-dependent kinase 8 (CDK8) inhibitors reduces their potential to migrate ...
Measurement science of the androgen receptor splice variant-7 protein in primary and castration-resistant prostate cancer tissue. Quality of life differences for LHRH-antagonist versus LHRH-agonist in ...
F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have discovered new heteroarylphenyl ether derivatives acting as cyclin-dependent kinase CDK8/cyclin C inhibitors. As such, they are reported to be ...
Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced that it has successfully discovered a potent, selective, and ...
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