Cancer cell biology unravels the molecular and cellular underpinnings of tumour formation, progression and metastasis. At its core, cancer arises as a result of dysregulated cell cycle control, ...

The field of regulated cell death has undergone a transformative shift with the discovery of novel modalities beyond apoptosis, such as ferroptosis, which ...

When the team knocked out the P2Y2 receptor in drug-resistant cancer cells, it led to an almost complete loss of the mutant EGFR protein.

Cancer cells undergo physically constraining processes, such as intravasation, extravasation, and tissue infiltration, that lead to acute mechanical stress. How mechanical confinement rewires the ...

A team of Canadian scientists has uncovered a new way to slow the growth of glioblastoma, the most aggressive and currently incurable form of brain cancer—and identified an existing medication that ...

How could patients with advanced breast cancer survive more than twenty years after a simple vaccine trial? This medical observation piqued the curiosity of scientists, who decided to reexamine ...

The field of cancer biology has recently recognized the significance of immunogenic cell death (ICD), a process by which dying cells emit alarm ...

Circulating tumor cells were first described in 1869 by Thomas Ashworth, an Australian pathologist who observed them in a peripheral blood sample taken from a patient with metastatic cancer. 1 They ...

A new AI tool, AAnet, has discovered five distinct cell types within tumors, offering a deeper look into cancer's inner diversity. This insight could transform how we treat cancer, enabling more ...

The Undergraduate Cancer Biology Society (UCBS) was started in 2022 with inaugural President Sarah Elimam. Now our third year as a UAB Registered Student Organization, UCBS is excited to continue its ...