Recommendations for Interventional Trials (SPIRIT) 2025 guidelines published in The Lancet and commend the efforts to enhance transparency and rigour in clinical trial protocols.1,2 Accurate and ...

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The first issue of Elsevier's new open access journal Contemporary Clinical Trials Communications features a new method to make cancer clinical trials more effective, a better way of determining ...

Phase 2 clinical data for coramitug, a potential first-in-class amyloid depleter antibody, for the treatment of ATTR-CM published in Circulation.

Clinical trials move through four structured phases, from safety testing to long-term effects. Adaptive, basket, and umbrella trials are making cancer research faster and more flexible. Molecular ...

These results suggest that “clinicians may be unaware of important clinical trial limitations identified by the FDA when making prescribing decisions." A majority of cancer drugs approved in the US ...

Prothena (PRTA) announced the publication of Phase 2 clinical trial data for coramitug for the treatment of ATTR amyloidosis with cardiomyopathy ...