The Indianapolis Colts' season is one of disappointment, but they can still end with an upset over the Houston Texans.

Get the best Colts vs. Texans predictions ahead of Sunday's AFC South finale at NRG Stadium. Free NFL picks for January 4.

USA Today's NFL experts make their picks for a Week 15 showdown between the Seattle Seahawks and Indianapolis Colts

After an 0-3 start, the Houston Texans are playoff bound. And depending on what happens in Week 18, still have a chance at winning a third straight AFC South title. Standing in their way is an Indianapolis Colts team playing for pride after an injury to Daniel Jones sent a once promising season into a tailspin.

The Indianapolis Colts venture into NRG Stadium in what could be a career-defining moment for one young quarterback. Houston’s elite defense will face a Colts offense led by rookie quarterback Riley Leonard that is looking for an answer at the quarterback position for 2026 and beyond.

Preview the Week 14 matchup between the Indianapolis Colts and Jacksonville Jaguars with predictions, odds, over/under, spread, betting lines and more.

The Indianapolis Colts' season could end the right way if these bold predictions come true vs. the Houston Texans.