Top artificial-intelligence models failed to predict the biological consequences of rewriting a virus's entire DNA code.

Researchers from the University of California San Diego and collaborators have identified a previously overlooked pattern of ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

Researchers have used AI to uncover the DNA signature of a key genetic “switch” involved in turning genes on. After analyzing ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...

The microbial toxin colibactin has just the right shape to snuggle up to DNA — but its embrace is unfortunately more cancerous than cozy. Colibactin is produced by bacteria in the gut and causes ...

The study highlights an important challenge in cancer research: even very large datasets can contain biological signals that ...