Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

A chemical modification of messenger RNA (mRNA) performs different functions depending on its location, according to a study published in the journal Molecular Cell. This modification is produced by ...

For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has ...

Engineered extracellular vesicles delivering full-length DMD mRNA restored dystrophin and improved muscle strength and ...

A new treatment platform developed by researchers at the University of Texas MD Anderson Cancer Center was able to deliver ...

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Malignant liver cancer is characterized by rapid tumour progression and a high mortality rate, whereas the molecular mechanisms underlying liver cancer initiation and progression are still poorly ...

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that ...

The tumor suppressor protein p53 plays a critical role in preventing cancer by regulating cell cycle, apoptosis, and genomic stability. However, mutations in the P53 gene are found in over 50% of ...

Introns are internal sequences that are removed from precursor mRNA transcripts by a two-step splicing process (see the figure). The first step involves cleavage of the phosphodiester bond between the ...

A new study has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA). For the very first time, a study led by Julian Chen and his group in Arizona ...

For the very first time, a study led by Julian Chen and his group in Arizona State University’s School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution, has ...