Researchers use long-read genome sequencing to discover 33% more structural variants and 38% more tandem repeats linked to autism spectrum disorder.

Kyoto, Japan -- The Human Genome Project generated the first sequence of the human genome, revealing a kind of blueprint of human biology. Two decades later, the field of gene regulatory networks ...

In 2021, a technology developed at University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Scientists looked at multiple techniques used to measure the modified viruses deployed in some gene therapy research and treatments. One technique, known as SEC-MALS, was the most precise and accurate ...

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and epigenetic state. By analyzing thousands of sequences, the method showed that ...

On a special episode (first released on June 20, 2024) of The Excerpt podcast: With the advent of CRISPR as a gene editing technology, there are new opportunities to develop breakthrough treatments ...

Complexities like these make it challenging to develop broadly applicable gene therapies for these disorders. Researchers at The University of Texas at Austin now have developed an improved method of ...

This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying gene cargoes because of their superior gene segmentation flexibility and ...