On December 19, 2025, the Centers for Medicare & Medicaid Services (CMS) released GLOBE (Global Benchmark for Efficient Drug Pricing Model) and GUARD (Guarding U.S. Medicare Against Rising Drug Costs) ...
On May 12, 2025, President Trump issued an Executive Order entitled “Delivering Most-Favored-Nation Prescription Drug Pricing to American Patients” in which he instructed his Administration to create ...
Federal health officials are proposing two mandatory payment models aimed at narrowing the gap between U.S. prescription drug prices and those paid in other developed countries, as Medicare spending ...
CMS’s proposed GLOBE and GUARD models represent an evolution in the Trump Administration’s approach to international reference pricing. However, their operational differences underscore the ...
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