GEN

Integrative Exome Sequencing and Machine Learning Identify New Genes Contributing to Systemic Sclerosis Risk

Scientists at the Baylor College of Medicine and collaborating institutions used complementary approaches that integrate exome sequencing and evolutionary action machine learning to identify protein ...
ascopubs.org

Paired matched normal sequencing to accurately identify somatic clonal hematopoiesis mutations (CHm) in solid tumor tissue and plasma specimens.

ctDNA as a biomarker in phase II study of tepotinib in advanced solid cancers with MET exon 14 skipping mutation or amplification (KCSG AL19-17). Characterization of molecular response and progression ...
Nanowerk

Next-Generation Sequencing in Genomics and Clinical Research

This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...
JSTOR Daily

Dynamic Linear Model for the Identification of miRNAs in Next-Generation Sequencing Data

This is a preview. Log in through your library . Abstract Next-generation sequencing technologies are poised to revolutionize the field of biomedicai research. The increased resolution of these data ...
EurekAlert!

AmproCode: an unprecedent amplifiable protein identification method towards next generation protein sequencing techniques

In the workflow of AmproCode, each type of the selected residues on peptide or protein samples can be respectively modified by the DNA barcode, and the composition code which is the relative ratio of ...
ascopubs.org

Efficacy of next-generation genomic sequencing (NGS) applied to cerebrospinal fluid (CSF) in the identification of actionable mutations in Mexican patients.

Marrow-ablative consolidation chemotherapy (HDCT) to decrease the development of choroid plexus carcinoma (CPC) specific relapse in high-risk TP53-mutated (germline or somatic) young children with ...
EurekAlert!

Pediatric Investigation review highlights the future of newborn screening with next-generation sequencing

Routine newborn screening (NBS) has transformed early disease detection. However, traditional biochemical tests limit the ...