Phosphatidate phosphatase (PAP) enzymes play a pivotal role in lipid metabolism, acting as a control point that directs metabolic flux between membrane phospholipid synthesis and the production of ...

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren’t completely sure why. They may have a better idea now, ...

An enzyme in the liver may partly explain sex differences in the body's handling of cholesterol and the risk of developing ...

This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells ...

Researchers from the National Institute for Physiological Sciences/the Exploratory Research Center on Life and Living Systems (ExCELLS)/the Graduate University for Advanced Studies (SOKENDAI) in Japan ...

For decades, we've been told “Lower LDL is Better.” But what if, in our myopic obsession with LDL and ApoB, we’ve missed a ...

Scientists at UC Irvine have found a way to potentially reverse age-related vision loss by targeting the ELOVL2 “aging gene” and restoring vital fatty acids in the retina. Their experiments in mice ...

An experimental drug may in future provide a new form of protection for people with celiac disease. According to an ...

A 4-week trial on 'Navelina' oranges shows potential effects on lipid metabolism in fatty liver disease, revealing intriguing ...

How the body efficiently shifts metabolism after fasting may be key to improving health, UTSW-led research suggests.