The glycosylation mechanisms in Streptococcus bacterial adhesins constitute a complex post-translational modification system that is vital for bacterial adhesion, biofilm formation, and pathogenicity.

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...

This finding, published in the Journal of Cell Biology, reveals a novel regulatory mechanism for sugar-donor levels. Dolichol-linked oligosaccharides (DLOs) are the main sugar donors for a key life ...

NT-proBNP is a cornerstone biomarker in the diagnosis and management of heart failure. Despite its widespread use, important biological and analytical challenges remain. One of the most significant is ...