Hopewell-based team delivers on ProBio's promise of speed, quality, and reliability—offering a transparent, fixed-cost model and ≥85% supercoiled plasmid DNA in record time for clinical programs. The ...

The use of in vivo electroporation (EP) as a therapeutic gene delivery approach has been successfully used in a variety of applications including cancer therapy and the regulation of protein levels to ...

Success in gene and cell therapy is driving demand for plasmid DNA which is a key reagent to produce viral vectors, both for commercial products as well as the breadth of different vectors for the ...

In the development of DNA vaccines and cell and gene therapies, manufacturing plasmid DNA creates a crucial bottleneck. Such a slowdown could intensify with the market for manufacturing DNA plasmids ...

Plasmid DNA isolation is an important technique in molecular biology, however, achieving effective high-throughput automation of this method has proven to be challenging. Analytik Jena and SynbiCITE ...

A team from Oregon State University has developed a comprehensive understanding of plasmid transfer in Agrobacterium. The strategy provided a means of inferring an evolutionary understanding of the ...

From gene therapy to vaccine development, plasmids are vital tools — but only if they’re designed, optimized, and verified with precision. Advances in codon optimization, long-read sequencing, and ...

Researchers have engineered a plasmid to remove an antibiotic resistance gene from the Enterococcus faecalis bacterium, an accomplishment that could lead to new methods for combating antibiotic ...

Scientists have reported large DNA structures in some archaea that defy easy categorization. When the microbiologist Jillian Banfield and her colleagues started combing through samples of mud from ...