The virus causing the ongoing COVID-19 pandemic, SARS-CoV-2, has spread far more quickly than any other coronavirus in recorded history. Why is it so contagious? One possibility is that its spike ...
Researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a cure. Case Western ...
Daniel Ojeda Juarez, a postdoctoral researcher at UC San Diego, explores the link between protein aggregation and cognitive ...
Scientists have detected abnormal prion protein in the skin of several people who died from Creutzfeldt-Jakob disease (CJD). The scientists also exposed healthy mice to skin extracts from two CJD ...
New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, MD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that ...
Close-up on three ropes and marine knots isolated on white background. Each is photographed separately. Prion diseases are rare but deadly neurodegenerative brain diseases that result from misfolding ...
CLEVELAND - A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy (VPSPr), as it has been named, is the second type of complete sporadic disease to be ...
The misfolding of proteins and their subsequent deposition as amyloid in peripheral nerves lead to sensory and autonomic neuropathy A new hereditary form of neuropathy, prion protein (PrP) systemic ...
Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein ...
Prion diseases are progressive nervous system diseases which always have a fatal outcome. They are transmissible and affect many mammals. They are also called transmissible spongiform encephalopathies ...
Chronic wasting disease (CWD) is a contagious neurological disorder that affects deer, elk, reindeer, and moose that leads to degeneration of brain tissue. Symptoms in infected animals include ...