Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity ...

The so-called ticking biological clock has been framed largely as a concern for women. We talk about egg freezing, ovarian ...

Key opportunities lie in next-generation sequencing methods, with hospitals as major end-users and North America as a ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

April 14, 2025 – Genome Research (https://genome.org) publishes a second special issue highlighting advances in long-read sequencing applications in biology and medicine. In this second Special Issue, ...

Traditional PCR systems require users to set a specified number of cycles according to the assay and the input amount. As a result, input material must be quantified, and samples of varying inputs ...

A study finds that brief immune stress in male mice can leave lasting metabolic and behavioral effects in offspring through ...