Optimizing CAR T-cell therapy to tackle solid tumors

In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite ...
Nature

Innovative CAR-T therapy destroys cancer cells without dangerous side effects

A new generation of engineered immune cell destroys cancer cells in mice 1 as effectively as conventional CAR-T-cell ...
The Brown Daily Herald

80% of the population is estimated to carry this herpesvirus. Here’s how these nonclassical immune cells might fight it.

A Brossay Lab study reveals how nonclassical CD8+ T cells can be activated by molecules that go undetected by classical CD8+ ...
Medical Xpress

CAR T cells with boosted BACH2 protein can fight cancer more effectively

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes engineered cancer-fighting immune cells behave more like stem cells, improving ...
FierceBiotech

In 2 papers, Nobel winner debuts technique to turn rogue T cells into their own treatment

Even for a newly minted Nobel laureate, downtime is hard to find. Just a few weeks after winning the 2025 Nobel Prize in Physiology or Medicine for his discovery of regulatory T cells or Tregs, ...
Medscape

CAR T-Cell Pioneer Plots Technology’s Next Steps

Renier Brentjens, MD, PhD, one of the pioneers in the development of chimeric antigen receptor (CAR) T-cell therapy, is poised to see the technology take its next big leap, with researchers testing ...
News Medical

EchoBack CAR T-cells could be a game changer in cancer immunotherapy

Imagine a super-charged immune cell that can launch a focused attack on stubborn solid tumors - a smart fighter that destroys cancer cells for days without tiring. USC biomedical engineers have made ...