A gene borrowed from the naked mole rat, an animal famous for extraordinary longevity and disease resistance, helped mice live a little longer and stay healthier, pointing to a surprising biological ...

RNA therapeutics target translation rather than DNA, aiming to correct shared protein production errors. By enabling cells to read through premature stop codons, engineered tRNAs could restore ...

Penn Gene Therapy Program Director James Wilson will depart the University, and the functions and assets of Penn Medicine’s Gene Therapy Program will be transferred to two new for-profit companies: ...

Lexeo Therapeutics is teaming up with Big Pharma Johnson & Johnson's unit Abiomed to tap its Impella heart pump technology in search of a potentially safer and more effective route for cardiac genetic ...

James Chappell, associate professor of biosciences and bioengineering at Rice University. In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic "base pairs" to a new level of precision, opening the door to safer, more ...

A novel CRISPR-based technology can spread within bacterial populations to eliminate antibiotic resistance. In a potential breakthrough for tackling antibiotic resistance, researchers from the ...