Systemic to pulmonary arterial shunts are surgically created connections between the aorta and a pulmonary artery in children with cyanotic congenital heart disease, such as tetralogy of Fallot or ...

We previously reported on the partial prevention of experimental shunt-induced pulmonary arterial hypertension (PAH) by the nonselective endothelin (ET) ET-A/ET-B receptor antagonist bosentan. As the ...

Babies with moderate to severe congenital heart disease usually require adequate blood supply to the lungs for survival, until proper surgery plan is adopted. In a recent study, pediatric researchers ...

THERE is now general agreement that closure of a defect of the ventricular septum is indicated in a patient with severe pulmonary hypertension when there is a large left-to-right shunt. It is equally ...

A patient with pulmonary arterial hypertension (PAH) who received a modified Potts shunt exhibited improved quality of life and exercise capacity after 1 year. A case report published in ERJ Open ...

The National Institute for Clinical Excellence is examining balloon angioplasty of systemic to pulmonary arterial shunts and will publish guidance on its safety and efficacy to the NHS in England, ...