RNAi is mediated by the enzymatic processing of long double-stranded RNA (dsRNA) into short-interfering RNA (siRNA)with sequence homology to the target mRNA. These siRNA molecules associate with a ...

The discovery of RNAi dates back to the 1990s when researchers observed unexpected gene silencing in plants and fungi. In 1998, Andrew Fire and Craig Mello published a groundbreaking study ...

This article is part 2 of a series on next-generation mRNA vaccines. The first installment can be read here. The unprecedented speed with which we developed vaccines to help us control and curb the ...

RNA, or ribonucleic acid, is a essential biological molecule that plays a crucial role in various cellular processes. It is a polymeric molecule composed of nucleotides, each containing a ribose sugar ...

(A) Pseudogenes can arise through the copying of a parent gene by duplication or by retrotransposition. An antisense transcript of the pseudogene and an mRNA transcript of its parent gene can then ...

Many novel designs and drug delivery systems have emerged over the past few years, allowing scientists to envisage the application of medicine based on ribonucleic acid (RNA) in the treatment, ...

Life may have begun when RNA molecules began to replicate themselves, and now we’ve finally found an RNA molecule that is very close to being able to do this ...

Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting hepatic ...

A new case report was published in Volume 17 of Oncotarget on February 6, 2026, titled “Exploring the potential link between ...

Wave Life Sciences has the fate of its lead RNA editing candidate back in its own hands. | Wave Life Sciences has the fate of its lead RNA editing candidate back in its own hands. GSK has decided not ...