Does using alcohol, nicotine, or cannabis engender addiction by changing the structure of brains, or does the structure of brains incline some people toward using those substances? In standard brain ...

People with substance use disorder—whether addicted to alcohol, cocaine, heroin, or nicotine—share a strikingly similar ...

Experts are already treating addicted people with at-home neuromodulation devices to control cravings, and the future is ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

While most prior studies have focused on brain-centric models of reward, some work has shown that gut-vagal signals have an effect on food-driven dopamine activity and eating behaviors. Yet it was ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

Consider someone addicted to alcohol, drugs, or a behaviour like gambling. Why do they continue, even when they say they want to stop? It’s a question that highlights a fundamental disconnect: the gap ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...