Cell cycle deregulation is a common feature of human cancer. Cancer cells frequently display unscheduled proliferation, genomic instability (increased DNA mutations and chromosomal aberrations) and ...
2 Department of Academic Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK 3 NIHR Birmingham Biomedical Research Centre, University of Birmingham and University Hospitals ...
Colorectal cancer (CRC) is currently ranked as the third most frequent human cancer and the fourth leading cause of cancer-related deaths worldwide. Macrophages and immune cell subsets infiltrate the ...
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