Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that ...

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks associated with exposure. In recent years, as part of efforts to reduce animal ...

Scientists have developed a functional human hepatic tissue in a mouse host. The human hepatic tissue, in the mice, is composed of human hepatocytes and non-parenchymal cells (NPCs) including human ...

Leveraging human organoid-based mechanistic investigation, researchers reveal how an immunosuppressive drug, antithymocyte ...

Of all the organs, the liver is most susceptible to drug toxicity. Drug-induced liver injury (DILI) is a leading cause of drug attrition, with over 750 FDA-approved drugs known to have a level of DILI ...

In the new approach, the pig liver remained outside the patient’s body, significantly lowering the risk of immune rejection.

Chinese researchers are reporting new steps in the quest for animal-to-human organ transplants — with a successful pig kidney transplant and a hint Wednesday that pig livers might eventually be useful ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...

A man lived for 171 days with a genetically modified pig liver, the greatest advance to date in xenotransplantation.

We’ve reached a new frontier in organ transplantation. In a medical first, scientists announced this week that they successfully kept a genetically modified pig liver functioning inside a human ...