Most bacteria, including many bacterial pathogens, are surrounded by an outer protective layer of sugar molecules, known as a ...

Therapeutic targeting of the AhR-Siglec-15 axis reveals potent efficacy against SHH medulloblastoma in preclinical models.

The enzyme Na⁺-NQR is a sodium pump that drives the respiration of many marine and pathogenic bacteria. Using redox reactions ...

Siglec-15 has traditionally been understood as an immune checkpoint molecule, primarily located on the cell membrane where it suppresses T-cell function. However, the new research revealed that in SHH ...

Men tend to lose the Y chromosome from their cells as they age. But because the Y bears few genes other than for male ...

From molecular chaperones to mitochondrial failure, discover how heat reshapes the human transcriptome and drives the biological cascade that links rising temperatures to organ injury and public ...

Living organisms share an ancestor called the last universal common ancestor, or LUCA. LUCA is estimated to have lived ...

The neuron’s inner scaffold, once viewed as static support, now looks like a gatekeeper. Research findings are available online in the journal Science Advances. The original story “ ‘Gatekeeper’ ...

A long-standing mystery in bile acid biology has been solved. Bile acids are often introduced as digestion helpers, but they are also powerful chemical messengers that help coordinate metabolism ...

NQR is a sodium pump that drives the respiration of many marine and pathogenic bacteria. Using redox reactions, the process of exchanging electrons between materials, it powers the transportation of ...