Gut

Norepinephrine promotes tumour cell aggressiveness and NK cell ferroptosis via ADRB2 in intrahepatic cholangiocarcinoma with perineural invasion

Background Sympathetic signalling plays a critical role in the initiation and progression of various malignancies. However, ...
Gut

Loss of sinusoidal endothelial identity: RAP1A at the crossroads of capillarisation and liver fibrosis

Liver fibrosis represents a serious worldwide health issue with a prevalence of around 5% in general populations.1 The most ...
gut.bmj

Spatially restricted tumour-associated and host-associated immune drivers correlate with the recurrence sites of pancreatic cancer

Correspondence to Dr Eva Karamitopoulou, Institute for Tissue Medicine and Pathology, University of Bern, Bern 3012, Switzerland; eva.diamantis{at}unibe.ch Conclusions Our findings demonstrate ...
gut.bmj

Cholesterol crystallisation in bile

Professor G P vanBerge-Henegouwen, Department of Gastroenterology, University Hospital Utrecht, PO Box 85500, Utrecht, The Netherlands. If you wish to reuse any or ...
gut.bmj

Low risk of covid-19 transmission in GI endoscopy

Reported experience from the recent worldwide COVID-19 outbreak suggests that GI endoscopy is a potential source of infection for healthcare workers (HCW); less is known about patient risk through ...
gut.bmj

Limited therapeutic efficacy of pioglitazone on progression of hepatic fibrosis in rats

1 Gastroenterology Unit, Université Catholique de Louvain (UCL), Brussels, Belgium 2 Pathology Unit, Université Catholique de Louvain (UCL), Brussels, Belgium Correspondence to: Professor I Leclercq ...
gut.bmj

Inflammation of the gastro-oesophageal junction (carditis) in patients with symptomatic gastro-oesophageal reflux disease: a prospective study

Department of Medicine, Division of Digestive Diseases and Gastroenterology, UCLA Medical Centre and Beth Israel Deaconess Medical Centre, Los Angeles, California, USA Dr T Lembo, Beth Israel ...
gut.bmj

Association between delayed gastric emptying and upper gastrointestinal symptoms: a systematic review and meta-analysis

Background The relationship between delayed gastric emptying and upper GI symptoms (UGI Sx) is controversial. Objective To assess association between gastric emptying and UGI Sx, independent of ...
gut.bmj

Cyclooxygenase 2—implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives

Cyclooxygenase (COX), the key enzyme for synthesis of prostaglandins, exists in two isoforms (COX-1 and COX-2). COX-1 is constitutively expressed in the gastrointestinal tract in large quantities and ...
gut.bmj

Chronic liver disease negatively affects outcome in hospitalised patients with community-acquired pneumonia

We read with great interest the article by Fernández and colleagues1 which identifies bacterial infections, including pneumonia, not only as a trigger, but also as a common complication of ...
gut.bmj

IDDF2025-ABS-0356 Catenibacterium mitsuokai promotes hepatocellular carcinogenesis by binding to hepatocyte and generating quinolinic acid

2 Institute of Digestive Disease and the Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong ...
gut.bmj

Infection rate and spontaneous seroreversion of anti-hepatitis C virus during the natural course of hepatitis C virus infection in the general population

1 Department of Virology, Istituto Superiore di Sanità, Rome, Italy 2 Department of Epidemiology, Istituto Superiore di Sanità, Rome, Italy Background: Hepatitis C virus (HCV) infection is common ...