RMD Open

Sustaining remission in rheumatoid arthritis: the role of clinical deep remission and its implications for drug tapering

Objective While sustained remission is the treatment goal for rheumatoid arthritis (RA), its long-term remission remains ...
rmdopen.bmj

Factors associated with radiographic progression of hand osteoarthritis over 2 years

Purpose To characterise radiographic progression over 2 years and associated characteristics in patients with hand osteoarthritis. Methods Baseline and year 2 data from the Hand OSTeoArthritis in ...
rmdopen.bmj

Safety of mycophenolate mofetil in systemic lupus erythematosus maintenance therapy: insights from the LUNA registry in a nationwide prospective cohort study

Objective We aimed to compare the incidence of severe infections between mycophenolate mofetil (MMF) and other immunosuppressants in patients with systemic lupus erythematosus (SLE) on maintenance ...
rmdopen.bmj

Early methylprednisolone pulses and prevention of long-term damage accrual in active systemic lupus erythematosus: a propensity score analysis of the Lupus–Cruces–Bordeaux ...

Objective Methylprednisolone pulses (MP) help achieve prolonged remission in patients with moderate–severe systemic lupus erythematosus (SLE), but their potential effect in reducing damage accrual has ...
rmdopen.bmj

Cryoneurolysis versus radiofrequency ablation outcome on pain experience in chronic low back pain (COPE): a single-blinded randomised controlled trial

Objective A comparison of cryoneurolysis or radio frequency (RF) with placebo in patients with facetogenic chronic low back pain (LBP) for patient global impression of change (PGIC), pain intensity, ...
rmdopen.bmj

Effect of high-intensity interval training in physiotherapy primary care for patients with inflammatory arthritis: the ExeHeart randomised controlled trial

Objectives To assess the effect of high-intensity interval training (HIIT) delivered in physiotherapy primary care on the primary outcome of cardiorespiratory fitness (CRF) in patients with ...
rmdopen.bmj

Machine learning-based multiclass model for autoimmune disease diagnosis and classification through nailfold videocapillaroscopy features

Objective To develop and validate a predictive model for distinguishing controls (Ctr), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) based on nailfold videocapillaroscopy (NVC) ...
rmdopen.bmj

MRI of shoulder girdle in polymyalgia rheumatica: inflammatory findings and their diagnostic value

Background Non-synovial inflammation as detected by MRI is characteristic in polymyalgia rheumatica (PMR) with potentially high diagnostic value. Objective The objective is to describe inflammatory ...
rmdopen.bmj

Benefit–risk analysis of upadacitinib versus adalimumab in patients with rheumatoid arthritis and higher or lower risk of cardiovascular disease

Objectives Evaluate the risks and benefits of upadacitinib 15 mg vs adalimumab in rheumatoid arthritis (RA) patients with an inadequate response to methotrexate based on cardiovascular (CV) risk.
rmdopen.bmj

Reliability of the OMERACT Giant cell arteritis Ultrasonography Score (OGUS): results of a patient-based exercise involving experts and non-experts in vascular ultrasonography

Objective To test the reliability of the Outcome Measures in Rheumatology Giant cell arteritis (GCA) Ultrasonography Score (OGUS) and other composite scores in a patient-based exercise involving ...
rmdopen.bmj

Predictors of a successful glucocorticoid tapering and withdrawal in an inception cohort of patients with lupus nephritis and associations with long-term outcomes and damage ...

Objectives The optimal duration of glucocorticoid (GC) treatment in lupus nephritis (LN) remains unclear. We examined predictors of GC tapering and discontinuation (D/C), flares during tapering and ...
rmdopen.bmj

Spontaneous resolution of acute gout: mechanisms and therapeutic targets

Gout is a common inflammatory arthritis that has been increasing in both prevalence and incidence. Consequently, management of refractory and chronic gout has been gaining attention. Onset of gout is ...