Millions of Americans across the country are on alert for a severe weather outbreak as violent, long-track tornadoes with damaging winds of up to 80 mph and large hail are expected across the Midwest and South with the cross-country storm moving east.

Large and destructive tornadoes are carving paths of destruction across the South for the second day in a row.

Multiple people have died amid an outbreak of severe weather across the South that forecasters warn could include "violent" tornadoes, high winds, thunderstorms and flash flooding on Saturday. Two people died and others were injured in a suspected tornado that touched down in the Bakersfield area of southern Missouri,

Tornadoes whipped through Missouri on Friday night, ripping apart homes, businesses, and the electrical system. Gov. Mike Kehoe’s Office says at least 12 people have been killed and one person is still missing from the severe weather.

Numerous significant tornadoes are expected Saturday afternoon and evening, with the highest risk across several states in the Deep South, forecasters say.