"By increasing BMP4, we can increase the metabolic rate, but we only see this in initially lean mice. Overweight mice proved to have a BMP4 resistance, which is also an important finding," says Jenny ...

Local progenitor cells shape the neoplastic vasculature and promote brain tumor growth. This is an ASCO Meeting Abstract from the 2021 ASCO Annual Meeting I. This abstract does not include a full text ...

Activation of the BMP4 signalling pathway presents a new therapeutic strategy to combat metastatic breast cancer, a disease that has shown no reduction in patient mortality over the past 20 years.

Bone Morphogenetic Protein 4 (BMP4) is a growth factor belonging to the TGF-beta superfamily. It plays a crucial role in various developmental processes, including neurogenesis, vascular development, ...

BMPER attenuated PI3K/AKT signaling and suppressed BMP4-driven smooth muscle activation in models of PAH. BMPER overexpression mitigated the vascular remodeling that characterizes pulmonary arterial ...

There was no weight gain, despite a higher energy intake, and insulin sensitivity was increased. These are the results from experiments on mice that had elevated levels of the protein BMP4 following ...