CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations associated with the strategy, including off-target DNA editing. A group of ...

Genetic disorders occur due to alterations in the primary genetic material—deoxyribonucleic acid (DNA)—of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid ...

With further optimization and safety evaluation, this CRISPR–Cas3 can be established as a new and safer platform for genome-editing-based therapies, providing patients with durable, possibly one-time ...

Researchers from Japan have established a new in vivo genome-editing system, CRISPR–Cas3, as a promising therapeutic approach for ATTR Genetic disorders occur due to alterations in the primary genetic ...

As vehicles grow more software-dependent, repairing them has become harder than ever. A bill in the US House called the Repair Act would ease those restrictions, but it comes with caveats. Every time ...

Gear-obsessed editors choose every product we review. We may earn commission if you buy from a link. Why Trust Us? The Takeaway: All it takes is a wayward rock kicked up in traffic to ruin an evening, ...

WASHINGTON — A defense policy bill expected to be voted on this week does not include provisions that would have ensured the military’s ability to purchase the technical data, parts and information ...

Series: Military Readiness Reform – Part I: The Right to Repair For years, service members have been limited in what they can fix, even when they know how. A broken part often meant waiting for a ...

The state leads the country in “repair cafes,” which bring neighbors together while keeping all manner of items out of the trash. By Hiroko Tabuchi Photographs by Lila Barth 50 States, 50 Fixes is a ...

The Repair App is a new platform that connects trusted repair service providers with people who need their stuff fixed. It couldn’t come at a better time for economically strapped consumers. A new app ...