When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

Scientists are exploring how DNA’s physical structure can store vast amounts of data and encode secure information.

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a double helix. That picture is still right, but it is no longer enough.

DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study. DNA can mimic protein functions by folding into elaborate, three-dimensional ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...