Learn how researchers at St. Jude, led by Hai Dao, PhD, discovered the mechanisms behind PARP1-mediated DNA repair.

Researchers say ‘AI worms’ could soon infiltrate internet-connected devices amid calls for increased guardrails Anthropic is warning that some of its artificial intelligence models could soon become ...

Anthropic described how AI models could infiltrate internet-connected devices and use their computing power to run themselves and spread to other devices. The AI model would be "challenging to shut ...

Faithful DNA replication requires not only copying genetic information but also restoring the packaging and organization of DNA, particularly within highly compact heterochromatin regions. We show ...

It’s tricky to make an exact copy of yourself. Or at least it is for cells undergoing mitosis, where cells replicate everything inside of them, including their neatly packaged DNA, then split in half.

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would later reshape biology and our understanding of life itself. A ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Back in high school chemistry, I remember waiting with my bench partner for crystals to form on our stick in the cup of blue solution. Other groups around us jumped with joy when their crystals formed ...

Leading Manchester United’s academy is no ordinary backroom role. The club’s heritage of developing young talent is unparalleled in English football, so whoever is tasked with running it has ...

Accurate genome duplication is essential for all living cells. In Escherichia coli and most other bacteria, a circular chromosome is replicated bidirectionally at high speed. Two replisomes, assembled ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...