Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...
Dr. Comfort is a historian of genetics who is completing a biography of James Watson. At first, James Watson terrified me. It was 1991 and my first day as the science writer at Cold Spring Harbor ...
The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...
The Microbial Insulin Production presentation provides an in-depth examination of recombinant insulin production and the challenges associated with meeting the rising demand for this critical ...
Twenty-seven entreaties drafted and endorsed following discussions at the 50-year anniversary summit of the 1975 Asilomar Conference on Recombinant DNA have been published and archived at Rice ...
The AI2Health cluster of the Ken Kennedy Institute and the Synthetic Biology Institute at Rice University hosted a debriefing and collaborative discussion session on the Spirit of Asilomar summit June ...
One of the greatest transformations in modern medicine arguably began with a corned beef sandwich. It was the late 1960s, and new Department of Medicine Chair Lloyd Hollingsworth “Holly” Smith Jr., MD ...
A new study in the journal Human Gene Therapy indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as ...
The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...
The year was 1975, before cell phones and email became ubiquitous, and Alex Capron remembers watching scientists lining up at a payphone during breaks at a conference. The payphone was in the main ...
Matthew Cobb is professor emeritus at the University of Manchester, UK, and author of The Genetic Age (Profile Books, 2022). On 24 February 1975, some 150 people met at the Asilomar Conference Grounds ...