BMJ11h
POS0107 IDENTIFICATION OF POTENTIAL GENES AND TREATMENT RESPONSE TO TOFACITINIB THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS
3 Institute for Medical Research, National Institutes of Health Complex, Allergy and Immunology Research Center, Selangor Darul Ehsan, Malaysia 4 Hospital Selayang, Department of Medicine, Selangor ...
BMJ22h
A randomised controlled trial of occupational therapy for people with early rheumatoid arthritis
Background: Occupational therapy (OT) aims at improving performance of daily living tasks, facilitating successful adjustments in lifestyle, and preventing losses of function. Objective: To evaluate ...
BMJ1d
Not only synovitis but also tenosynovitis needs to be considered: why it is time to update textbook images of rheumatoid arthritis
Correspondence to Professor Annette van der Helm-van Mil, Rheumatology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands; A.H.M.van_der_Helm{at}lumc.nl Rheumatoid arthritis (RA) is ...
BMJ1d
Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California, San Diego, California, USA Correspondence to Dr Michael ...
BMJ2d
Anti-endothelial cell antibodies in systemic sclerosis
Department of Internal Medicine/Division Clinical and Experimental Immunology, University Hospital Maastricht, Maastricht, The Netherlands Correspondence to Professor J W C Tervaert, Department of ...
BMJ2d
PPARγ preservation via promoter demethylation alleviates osteoarthritis in mice
Objectives Osteoarthritis (OA) is the most common degenerative joint disease in aged population and its development is significantly influenced by aberrant epigenetic modifications of numerous OA ...
BMJ2d
Validity, reliability, and applicability of seven definitions of hip osteoarthritis used in epidemiological studies: a systematic appraisal
1 Department of General Practice, Erasmus MC, Rotterdam, The Netherlands 2 Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands 3 Department of Rheumatology, Erasmus MC ...
BMJ5d
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritis
Correspondence to Dr Tristan Maerz, Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan, USA; tmaerz{at}med.umich.edu Objectives Synovium is acutely affected following joint ...
BMJ7d
Are patients with rheumatoid arthritis still at an increased risk of tuberculosis and what is the role of biological treatments?
Correspondence to Dr Elizabeth V Arkema, Clinical Epidemiology Unit, T2, Karolinska Institutet, Stockholm 17176, Sweden; Elizabeth.Arkema{at}ki.se Objective To estimate the risk of tuberculosis (TB) ...
BMJ13d
Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis
Objectives Alarmins S100A8/A9 regulate pathology in experimental osteoarthritis (OA). Paquinimod is an immunomodulatory compound preventing S100A9 binding to TLR-4. We investigated the effect of ...
BMJ13d
Treatment efficacy and safety of tofacitinib versus methotrexate in Takayasu arteritis: a prospective observational study
Objective To compare the treatment efficacy and safety of tofacitinib (TOF) versus methotrexate (MTX) in Takayasu arteritis (TAK). Methods Fifty-three patients with active disease from an ongoing ...
BMJ14d
Vascular occlusion for optimising the functional improvement in patients with knee osteoarthritis: a randomised controlled trial
Objectives Knee osteoarthritis (KOA) is a leading cause of global disability with conventional exercise yielding only modest improvements. Here we aimed to investigate the benefits of integrating ...