Skin manifestations are common in patients with SLE. A recent study reported increased site-specific recurrence of cutaneous lupus erythematosus (CLE).1 While this study included a proportion of ...
Background Current diagnosis of antiphospholipid syndrome (APS) relies on antiphospholipid antibodies (aPL) testing, but false-positive aPL results and asymptomatic aPL carriers pose significant ...
Objective To assess organ damage, with emphasis on the cardiovascular system, over the different stages of the disease in a large SLE cohort. Methods Multicentre, longitudinal study of a cohort of ...
Background SLE is a chronic autoimmune disease with heterogeneous manifestations. This study evaluated the discriminative value of complete blood count-derived biomarkers, including ...
The heterogeneity of lupus arthritis complicates clinical management and trial endpoints. Musculoskeletal ultrasound (MSK US), and MRI have been proposed as objective assessment tools. In a systematic ...
22 Historical aspects of B-cell depletion in SLE (8 October, 2025) ...
Haematologic involvement in patients with systemic lupus erythematosus (SLE) is very common. The principal cytopenias in lupus result in anaemia, white cell deficits and thrombocytopenia. Anaemia may ...
Case 1: A 35-year-old female with SLE and planning IVF pregnancy In October 2024 a 35-year-old female with systemic lupus erythematosus (SLE) was reviewed for planning of in vitro fertilization (IVF) ...
Case 1: A 20-year-old Caucasian female A 20-year-old Caucasian female presented with a malar rash, polyarthritis, Raynaud’s phenomenon, oral ulcers and pleurisy in November 1977. Serology revealed ANA ...
What have we learned from all randomized controlled trials with new agents added on to standard of care for the treatment of patients with systemic lupus erythematosus (SLE)? While positive studies ...
Introduction SLE is a chronic autoimmune disease characterised by multisystem involvement and fluctuating clinical course, often leading to permanent organ damage. Childhood-onset SLE (cSLE) tends to ...
Objective This study uses Mendelian randomisation (MR) to investigate the causal link between SLE and osteoporosis across different ethnic groups. Methods Genetic variants associated with SLE were ...
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