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心肌细胞(CM)是不可再生的。 自我更新的多能人类胚胎干细胞 (hESC) 可以分化为用于细胞疗法的 CM。 在成人CM中,Ca(2+)诱导的Ca(2+)通过兰尼碱受体(RyR)从肌浆网(SR)释放是兴奋-收缩耦合的关键。 因此,hESC 衍生的 CM 需要具有 ...
心肌细胞(CM)是不可再生的。 自我更新的多能人类胚胎干细胞 (hESC) 可以分化为用于细胞疗法的 CM。 我们最近报道,Ca(2+) 处理对于 hESC 衍生的 CM (hESC-CM) 的兴奋-收缩耦合至关重要,具有功能性但不成熟。 胞质Ca(2+)瞬时幅度 ...
Therapeutic Candidate or Device Autologous Human CD34+ HSC from Mobilized PBSC of Patients with Cystinosis Modified by Ex Vivo Transduction using the pCCL-CTNS Lentiviral Vector Indication Cystinosis ...
Josh Karam, Nimrah Ashfaq, Cynthia Benitez, Victor Morales, Elizabeth Partida, Michelle Hernandez, Jordan Yokoyama, Alyssa Villegas, Brielle Brown, Pooja Sakthivel, Aileen J Anderson, Brian J Cummings ...
Pursuant to Executive Order N-29-20, certain provisions of the Bagley-Keene Open Meeting Act are suspended due to a State of Emergency in response to the COVID-19 pandemic. Consistent with the ...
加利福尼亚州旧金山——当你需要钱时,你就去银行。 但是,当研究人员需要高质量的干细胞时,他们去哪里获取这些干细胞呢? 很快他们就可以前往加州干细胞机构加州再生医学研究所(CIRM)设立的干细胞库。 该机构的 ...
Research Objective Functional restoration following spinal cord injury using defined excitatory and inhibitory spinal interneuron progenitor cell transplantation Impact The development of a stem cell ...
Quest – Discovery Stage Research Projects University of California, Berkeley Scalable, Defined Production of Oligodendrocyte Precursor Cells to Treat Neural Disease and Injury $1,627,099 Tools and ...
La maladie coronarienne, entraînant un blocage du flux sanguin vers le cœur, est une cause majeure de crise cardiaque. L'âge et les blessures provoquent des changements structurels et fonctionnels ...
Research Objective We will identify SAR-CoV-2 T cell epitopes for vaccine development and specific TCRs for adoptive T cell therapy using a stem cell-based platform to generate specialized dendritic ...
Nos entristece profundamente saber del fallecimiento de un paciente que participaba en el ensayo clínico de fase 2 de Rocket Pharmaceuticals con RP-A501 para tratar la enfermedad de Danon. En nombre ...
SAN FRANCISCO, September 5, 2006 – The California Institute for Regenerative Medicine (CIRM) announced today that it has named Marcia Davey as Interim Financial Officer. The one-year appointment is ...