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  1. Major depressive disorder - Wikipedia

    Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [10] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or …

  2. Depression (major depressive disorder) - Symptoms and causes

    Oct 14, 2022 · Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble …

  3. Clinical Depression (Major Depressive Disorder): Symptoms

    Nov 30, 2022 · Clinical depression, also known as major depressive disorder (MDD), is a mental health condition that causes a persistently low or depressed mood and a loss of interest in activities that …

  4. Depression (Major Depressive Disorder): Symptoms and More

    Jul 5, 2025 · Major depressive disorder (MDD) is a common mood disorder characterized by persistent sadness and a loss of interest in activities, impacting mood, behavior, and physical functions.

  5. Major Depressive Disorder (MDD) - PsychDB

    Feb 27, 2024 · Major Depressive Disorder (MDD) is a mental disorder characterized by persistent, often daily, low mood and/or decreased interest (anhedonia). There are also associated neurovegetative …

  6. Major Depressive Disorder - PubMed

    Apr 10, 2023 · Major depressive disorder (MDD) has been ranked as the third cause of the burden of disease worldwide in 2008 by WHO, which has projected that this disease will rank first by 2030.

  7. Major Depressive Disorder (MDD) - MentalHealth.com

    Aug 7, 2025 · Major Depressive Disorder (MDD) is a common but serious mental health condition. This is more than just feeling sad or going through a rough patch; it’s a medical illness that causes a …

  8. Major Depressive Disorder: Symptoms, Causes, Treatment

    Dec 11, 2025 · What Is Major Depressive Disorder? Major depressive disorder (MDD) is a serious mood disorder causing mild to severe symptoms that persist for two weeks or longer and affect daily life.

  9. Major Depressive Disorder - NAMI

    When more severe symptoms like lack of energy and hopelessness develop in multiple areas of a person’s life along with persistent sadness over at least two weeks, they may be experiencing a …

  10. Back to Basics: A Refresher on Treating Major Depressive Disorder

    Jan 12, 2026 · Major Depressive Disorder (MDD) remains one of the most common and impactful conditions seen in primary care. While many of us treat depression daily, it is valuable to periodically …